Spontaneous seizures generated in rats by kindling: A preliminary report
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چکیده
Daily amygdaloid stimulation administered to rats at current levels initially too low to produce a motor response but high enough to produce an electrographic afterdischarge (AD) resulted in the progressive development and intensification of stimulus-induced epileptic activity (kindling). In contrsst to previous studies, however, stimulation was continued long after the point where the exacerbation of motor seizures (MSs) seemed complete. Several animals were stimulated for up to 7 months and, with continued stimulation, an epileptic syndrome characterized by spontaneous motor seizures was observed to develop.
منابع مشابه
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تاریخ انتشار 2013